July 02, 2008

Why Persistent Acid Reflux Sometimes Turns Into Cancer




New research from scientists at UT Southwestern Medical Center and the Dallas Veterans Affairs Medical Center emphasize the exigency of prevent even acerbic reflux while also uncovering tantalizing clue by means of the side of how standard acid reflux can pull potentially cancerous.



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"The research supports why it be critical to preclude reflux, because the more reflux you have and the longer you have it, the more it might persuade you to getting Barrett's esophagus.



So you want to mill that reflux," said Dr. Rhonda Souza, spine the finger at professor of axis prescription at UT Southwestern and head author of the treatise which appear in the American Journal of Physiology -- Gastrointestinal and Liver Physiology.



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Over juncture, the insistent acid hip bath can cause everyday skin-like cells in the esophagus to variation into tougher, more acid-resistant cells of the style found in the stomach and intestine, a criterion called Barrett's esophagus, explain Dr. Stuart Spechler, professor of internal medicine and pacesetter author of the paper. "Unfortunately, those acid-resistant cells be also more prone to cancer," Dr. Spechler said.



The CMREF research initiative is designed to patronage a network of multidisciplinary, collaborative transplant and research centers to study the origins of IPAH. A coordinate center will be responsible for the shape, running and analysis of the IPAH database.



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